Twitter moves fast, and if you don’t stay on top of it, you can miss a lot. I don’t follow a ton of people, but I combine it with topic searches. Here are a few things I’ve found that are worth your time and attention, especially if you’re into video games… development or playing:

• The 15 Greatest Sci-Fi/Horror Games for the Commodore 64 - http://moe.vg/bovATG 
  (via @jlist) 
  
• Practical Tactics for Dealing with Haters! - http://www.fourhourworkweek.com/blog/2010/05/18/tim-ferriss-scam-practical-tactics-for-dealing-with-haters/
  (via @The_Zman)
  
• Assassin’s Creed 2 + $10 Video Game Credit + $5 MP3 Credit - $24.99 on Amazon.com – http://amzn.to/bvRI9h
  (via @Assassin10k)
  
• Make Small Good – A design article about not trying to compete with ginormous AAA multimillion dollar titles. - http://www.gamasutra.com/blogs/AlexanderBrandon/20100518/5067/Make_Small_Good.php
  (via @Kei_tchan)
  
• (CW: Excellent article, I do this a lot in my roguelike games!) Purposes for Randomization in Game Design – http://bit.ly/cAH7PG 
  (via @gamasutra)