I have some questions running multiple Django sites on a VPS I have a server that uses openPanel to automatically create VirtualHosts within apache2. My ideal situation is that I would have multiple virtualenvs with different dependencies installed so the python dist-packages directory isn't contaminated for different Django sites. For example: /home/user/virtualenv1 /home/user/virtualenv2 My django applications reside at /var/www, so For example: /var/www/djangosite1 /var/www/djangosite2 Now I've read upon openPanel docs and figured out the best thing todo is create a django.conf file inside the mydomain.com.inc folder, which looks something like: /etc/apache2/openpanel.d/mydomain.com.inc/django.conf DocumentRoot /var/www/djangosite1/project WSGIScriptAlias / /var/www/djangosite1/project/wsgi.py WSGIDaemonProcess mydomain python-path=/home/user/virtualenv1/lib/python2.6/site-packages <Directory /var/www/djangosite1/project> Order allow,deny Allow from all </Directory> Alias /static /var/www/djangosite1/project/static-root Now my problem is that this setup seems unable to find the virtualenv site-packages thus not recognizing any dependencies available in the given virtualenv Also, commenting out this line doesn't seem to break or change a thing: WSGIDaemonProcess mydomain python-path=/home/user/virtualenv1/lib/python2.6/site-packages For example: > service apache2 start ImportError: No module named South When I install South outside the virtualenv everything works