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  • Get coordinates of beads covering the surface of a protein

    - by Hefeweizen
    Given a protein structure from the PDB, I would like to generate NS spheres of radius Rs which cover totally the protein surface. Given RS there, NS is the maximum number of spheres so they do not overlap. I would need the coordinates of the center of each sphere. Does anybody know if this has been implemented in some method / program? Or how to do it with scripting. Thanks

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  • who do you admire in a scientific/technical field [closed]

    - by Tshepang
    This off-topic item refers to people with major achievements in fields such as engineering, science, and mathematics. Here's my picks: Eric Drexler for his work on molecular nanotech. His book, Engines of Creations, is mind-blowing. Robert Freitas for his work on molecular nanotech. The breadth of his multi-volume book, Nanomedicine, is impressive. Richard Stallman for promoting Free Software.

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  • What Can You Do When You Need More Than Just CRM?

    - by charles.knapp
    Sometimes a company needs more than just CRM to grow profitably. What if you also need ERP for streamlining the rest of your operations? Unlike CRM-only companies, Oracle can help you - today. For example, Myriad Genetics was an early pioneer and is currently a global life sciences leader in the exciting field of molecular diagnostic products. To keep pace with company growth, Myriad needed to integrate disparate systems and automate paper-based processes. Furthermore, Myriad needed to increase sales pipeline visibility to maximize customer service. Myriad selected Oracle CRM On Demand and E-Business Suite ERP applications. As a result, Myriad standardized sales processes, ensured greater visibility into the pipeline, and improved customer service. Read more here about Myriad and their business results.

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  • What is a modern software engineer's resume supposed to look like? [on hold]

    - by willOEM
    My secondary education was primarily focused on the sciences (Molecular Biology and Bioinformatics), but now I work primarily as a software developer. I feel like my resume is totally inappropriate for my current career goals. Listing laboratory skills and accomplishments is not the same as listing software development skills and accomplishments. Oddly enough, I can't seem to find any resources for writing a engineer's resume online that aren't older than 5 years. GitHub and StackExchange profiles seem like as important resume items as anything, yet I don't know how to list them on a resume, or whether they are appropriate at all. So what is a modern software engineer's resume supposed to look like?

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  • The Ubuntu App Showdown -Specific software

    - by Stefanie
    I would like to participate the contest but I'm programming very specific scientific tools for the work in a molecular biological lab. I know that I won't win with such an app but it's a nice possibility to get into Qickly and Ubuntu Apps since I'm only programming for Windows at the moment. My question is, whether I have a possibility to explain what my software is doing and for what it is good in the lab. Also I have to provide some test data, that the jury can try it out. Is this possible and how I can submit those additional information?

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  • Recommended reading for bioinformatics

    - by Matt
    I'm keen on learning about bioinformatics. I am ideally looking for a short course introduction, with some practical tasks I can get my teeth into immediately to see if there is any interest in it for me. I already have a good understanding of molecular biology, so I should be able to skip most of the foundational work. Any suggestions?

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  • missing libjpeg.so.62 from ia32 shared library

    - by user170200
    I am trying to install a chemical/molecular biology modeling program called Molsoft ICM-Pro. Initially after downloading the program and trying to open, it gave me error messages that I was missing shared libraries, and after talking with my network administrator he recommended I install the ia32 shared libraries using sudo apt-get install ia32-libs Which gives sudo apt-get install ia32-libs Reading package lists... Done Building dependency tree Reading state information... Done ia32-libs is already the newest version. 0 upgraded, 0 newly installed, 0 to remove and 0 not upgraded. so I am assuming the libraries installed correctly, but now when I try to run the program I get this error: ubuntu:/home/reilly/icmd icm icm: error while loading shared libraries: libjpeg.so.62: cannot open shared object file: No such file or directory So my question is, where can I get the library containing libjpeg.so.62? Additionally, I was told I would need libXmu.so.6 and libtiff.so.3 . Is there a shared library that could be missing that would contain these files? I am an ubuntu noob, so sorry if the information I provided was unclear. Any help would be immensely appreciated! btw I am using ubuntu 12.04 dual boot with windows on an HP pavilion dv6

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  • Open Source Projects for Beginning Coders?

    - by MattDMo
    After working as a molecular biologist at the bench for many years, I lost my job last year and am thinking about a career change. I've been using open-source software and doing Linux system administration since the mid 90s, and have written/improved some small shell/Perl/PHP scripts, and am very comfortable building from source, but never progressed to creating non-trivial programs de novo. I want to move to actually learning real programming skills and contributing back to the community, with the possible eventual goal of getting into bioinformatics as a career in the future. I'm a stay-at-home dad now, so I have some time on my hands. I've done a lot of research on languages, and have settled on Python as my major focus for now. I'm set up on GitHub, but haven't forked anything yet. I've looked around OpenHatch some, but nothing really grabbed me. I've heard the advice to work on what you use/love, but that category is so broad that I'm having trouble finding any one thing to get started on. What are your suggestions for getting started? How do you pick a project that will welcome your (possibly amateurish) help? With a fairly limited skill set, how do you find a request that you can handle? What are common newbie mistakes to avoid? Any other advice?

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  • 1tera flop cluster?

    - by Adobe
    I want to buy a $40000 1 tera flop cluster to keep it in a room. What are the standard configurations? Cluster is supposed to do molecular dynamics simulations on biological systems. I'm proposed a 4 pc with 8 cores each by the selling company I'm deadling with. It looks like I also need infiniband. Does some one has an experience -- what phisical memory should I buy etc? I know things change very quickly... Still there might be a point or two to state. Edit: OS is supposed to be linux, application is gromacs.

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  • 1 tera flop cluster?

    - by Adobe
    I want to buy a $40000 1 tera flop cluster to keep it in a room. What are the standard configurations? Cluster is supposed to do molecular dynamics simulations on biological systems. I'm proposed a 4 pc with 8 cores each by the selling company I'm deadling with. It looks like I also need infiniband. Does some one has an experience -- what phisical memory should I buy etc? I know things change very quickly... Still there might be a point or two to state. Edit: Custer is supposed to run linux, and gromacs in it.

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  • Need help to install Ubuntu on Win7 Alienware M17xR3, installing not working

    - by Rodrigo
    Please I need help to install linux on my computer to start analyzing Next Generation Sequencing (molecular genetics) for my work. I've tried to install from all different ways and forms and it gave me different errors. First I will describe my system: Alienware M17x R3 Raid Drive 596GB (2x 298 GB) Windows7 primary partition C: The hardrive is divided in 3 primary partitions (can't do 4 don't know why) 1st: Fat16 no name capacity 40mbs almost not used (has files like command.com, dellbio.bin, dellrmk.bin and oobedone.flg) I dont know what this is for but is blocked and non system (Status:none). 2nd: Recovery NTFS 9GB (Status:system) and it seems to have boot files. 3rd: CD: Windos OS (status:boot). And I have 2 Logical drivers F: data for backup and games :D (300gb) G: For trying to install the Linux (Already tried with Fat32, Ext2, ext3 and ext4) Installing with Wubi on F: and G: Instalation looks good on windows ask to restart dos mode appears: try (HD0,0) non-ms:skip try (HD0,1) NTFS5: No Wibildr try (HD0,2) NTFS5: Error: "Prefix" is not set. Installing with Wubi on C: Installation looks good on windows ask to restart dos mode apears: Mount denied becouse NTFS volume is already exclusive opened, the volume may be already mounted or another software may use it which could be identified for example by the help of the 'FUSER' command Mount devdm-4 Could not find installation files /ubuntu/install custom-installation Run 'Chkdsk /r' on windows and restart...blablablalba... that should correct. done this didn't work. Tried installing with USB drive and after burning a CD with the Iso file download from the official website: I've tried the option to install along windows with a G: drive in FAT32, EXT2,3 and 4, I've tried to leave unallocated data, without the driver G at all... appears this everytime: http://i.stack.imgur.com/eo2Ie.png pres ok it ask me to: Not possible to install the boot loader at the location: specify new location: I've tried to select all the drivers non is accepted If I ask to continue without installing the boot loader he ask me to install later by myself which I'm trying to figure it out but I'm not really good to understand how ppl get to the programming part like a DOS to write down couse I'm a newb and I've dont work on dos or linux before... I've read that the boot loader has to be installed on the primary partition, but I'm not sure what I can delete from those 2 partitions that would let me get 1 extra... and it seems that the one that windows use is protected to write down so the software is not touching it... Please if someone have any idea to help me out... I've got a course tomorrow of how to use the software to analyze the data and I wanted to take my computer with me, so I've passed the last 3 days trying to search different ways to solve. My question is also post on the bugs.launchpad.net link here: lounchpad.net bug #882695

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  • OpenCL - incremental summation during compute

    - by user1721997
    I'm absolutelly novice in OpenCL programming. For my app. (molecular simulaton) I wrote a kernel for calculate intermolecular potential of lennard-jones liquid. In this kernel I need to compute cumulative value of the potential of all particles with one: __kernel void Molsim(__global const float* inmatrix, __global float* fi, const int c, const float r1, const float r2, const float r3, const float rc, const float epsilon, const float sigma, const float h1, const float h23) { float fi0; float fi1; float d; unsigned int i = get_global_id(0); //number of particles (typically 2000) if(c!=i) { // potential before particle movement d=sqrt(pow((0.5*h1-fabs(0.5*h1-fabs(inmatrix[c*3]-inmatrix[i*3]))),2.0)+pow((0.5*h23-fabs(0.5*h23-fabs(inmatrix[c*3+1]-inmatrix[i*3+1]))),2.0)+pow((0.5*h23-fabs(0.5*h23-fabs(inmatrix[c*3+2]-inmatrix[i*3+2]))),2.0)); if(d<rc) { fi0=4.0*epsilon*(pow(sigma/d,12.0)-pow(sigma/d,6.0)); } else { fi0=0; } // potential after particle movement d=sqrt(pow((0.5*h1-fabs(0.5*h1-fabs(r1-inmatrix[i*3]))),2.0)+pow((0.5*h23-fabs(0.5*h23-fabs(r2-inmatrix[i*3+1]))),2.0)+pow((0.5*h23-fabs(0.5*h23-fabs(r3-inmatrix[i*3+2]))),2.0)); if(d<rc) { fi1=4.0*epsilon*(pow(sigma/d,12.0)-pow(sigma/d,6.0)); } else { fi1=0; } // cumulative difference of potentials fi[0]+=fi1-fi0; } } My problem is in the line: fi[0]+=fi1-fi0;. In the one-element vector fi[0] are wrong results. I read something about sum reduction, but I do not know how to do it during the calculation. Exist any simple solution of my problem?

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  • Querying a 3rd party website's database from my website

    - by Mong134
    The Goal: To retrieve information from a 3rd party database based off of a user's query on my ASP.NET website The Details: I need to be able to search 3rd-party websites for information relating to pharmaceutical drugs. Basically, here's what I've been tasked with: a user starts entering the name of a drug they're using in their experiments, and while they're typing a 3rd party website (e.g., here or here) is queried and suggestions are made based based off of what they've typed. Once they've made a selection, certain properties (molecular weight, chemical structure, etc) are retrieved from the 3rd party database and stored in our database. PharmaGKB.org's search bar is pretty much what I need to implement, but I need to access a 3rd party db. The site that I'm working on is ASP.NET/C#. The Problem: I don't really know where to start with this. There's a downloadable Perl example at the bottom of the page here, but it didn't really help me all that much. I'm at a loss as to how to implement this, or even find information about how to do it. The AJAX toolkit was suggested, but I'm not sure if that will solve the issue. JavaScript is also being considered, but again, I'm not sure if that will be sufficient, either. Perl Example Connection As a mentioned, here is a snippet from the Perl example given on the Pharmgkb.org site: my $call = SOAP::Lite -> readable (1) -> uri('SearchService') -> proxy('http://www.pharmgkb.org/services/SearchService') -> search ($ARGV[0]); However, I'm not sure how to implement this is C#/ASP.NET/JavaScript. There's a question on Stack Overflow about embedding Perl in C#, but it require a C wrapper as well, and I don't think that three languages is necessary or wise to solve this issue.

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  • career advice for PhD scientist seeking to program?

    - by C SD
    I'm largely a self-taught programmer. In fact, I first started programming about half way through biophysics grad school, and even though I think I've done some pretty nice work, I've never worked as part of a 'serious' development team that had more than one or two other developers (and I wouldn't hesitate to call them equally inexperienced in software development as a profession). After finishing my PhD I applied to Google, on a lark, since I had some confidence in my abilities, if not necessarily my experience, and I was hoping to maybe slip in and absorb all the experience and talent I'd be surrounded with and become productive enough, quickly enough, that they wouldn't immediately regret their decision. I was excited to actually get invited to interview up at Mountain View (this was ~ mid 2008). Overall, my memory of the interview was very positive, but after close to a three month wait (is that normal?) they ended up turning me down. I wasn't too surprised or disappointed (aside from the uncomfortably long wait) given my unusual background and admitted lack of experience. I decided to continue as a postdoc, but focus on improving my skills rather than doing research. I've done about three years of that, and my honest assessment is that I've learned a ton more, but I really need more of a peer group to maintain or accelerate my growth. Google invited me to interview again about eight months ago, and the interview process went even better than the first time around (I thought), though they again declined to give me an offer. I have to admit this second rejection was much more discouraging. They had insisted I interview even after I mentioned to them that a move on my part was unlikely given that I had bought a house, gotten married, etc. since the first interview. I guess I was hoping they'd at least give me an offer that I could parlay into a more conventional, but still interesting, programming position close to home. So here I am, going on my third year out of grad school, a glorified postdoc and I'm starting to get pretty discouraged. Even though I could technically get 'back-on-track' for a career in science, I have been focusing the vast majority of this time on gaining programming experience rather than on research and publications. The problem is, whenever I look, most job listings have requirements that seem impossibly grandiose and I hesitate to apply. That, or the job/project seems incredibly dull. Ironically, applying to Google struck me as less intimidating. I suspect that either most people are just a lot less realistic than I am when it comes to assessing how long it will take for them to get up to speed, or they don't care; my fear is that I'm just woefully unqualified for any interesting, well paying work. IE: I'm confident I could switch fully back into C++ mode with a couple weeks work (I mostly use C,Python,C# daily) but I don't list myself as being 'proficient' in C++ on my CV, or applying for jobs that 'require' such knowledge. The few applications for which I did feel I was a legitimately good match have not elicited a response. I suspect the following things are potential problems with my application/CV and I would like feedback on: I don't have a CS degree. My BS was in biochemistry and molecular biology, my PhD in biophysics. I took a undergrad and grad level CS course at UCSD and completely killed them, but I don't know how to translate that to my CV effectively. I have a PhD, but it's not in CS... I've been debating if I should remove it from my CV, and wether or not it would then be misleading to list at least some of those years as some kind of 'programming' job (in many respects it was). I think there are sometimes strong stigmas associated with 'self-taught' programmers. I am certainly one of those. I even recognize that some of those stigmas hold a hint of truth, but I really do want to be an asset to a team. How do I communicate that even though I have been largely self-directing for ~8 years I can still take marching orders when needed? Do I just say so outright? Should I just become a lot less scrupulous about the whole process? anecdote: I have a friend who applied for positions where he completely fudged his qualifications to get past the first culling. He was much more honest and forthcoming about his actual qualifications when contacted and he still managed to get invited to a couple of interviews and even got some offers. His balls are larger than mine though.

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  • How can I extract paragaphs and selected lines with Perl?

    - by neversaint
    I have a text where I need to: to extract the whole paragraph under the section "Aceview summary" until the line that starts with "Please quote" (not to be included). to extract the line that starts with "The closest human gene". to store them into array with two elements. The text looks like this (also on pastebin): AceView: gene:1700049G17Rik, a comprehensive annotation of human, mouse and worm genes with mRNAs or ESTsAceView. <META NAME="title" CONTENT=" AceView: gene:1700049G17Rik a comprehensive annotation of human, mouse and worm genes with mRNAs or EST"> <META NAME="keywords" CONTENT=" AceView, genes, Acembly, AceDB, Homo sapiens, Human, nematode, Worm, Caenorhabditis elegans , WormGenes, WormBase, mouse, mammal, Arabidopsis, gene, alternative splicing variant, structure, sequence, DNA, EST, mRNA, cDNA clone, transcript, transcription, genome, transcriptome, proteome, peptide, GenBank accession, dbest, RefSeq, LocusLink, non-coding, coding, exon, intron, boundary, exon-intron junction, donor, acceptor, 3'UTR, 5'UTR, uORF, poly A, poly-A site, molecular function, protein annotation, isoform, gene family, Pfam, motif ,Blast, Psort, GO, taxonomy, homolog, cellular compartment, disease, illness, phenotype, RNA interference, RNAi, knock out mutant expression, regulation, protein interaction, genetic, map, antisense, trans-splicing, operon, chromosome, domain, selenocysteine, Start, Met, Stop, U12, RNA editing, bibliography"> <META NAME="Description" CONTENT= " AceView offers a comprehensive annotation of human, mouse and nematode genes reconstructed by co-alignment and clustering of all publicly available mRNAs and ESTs on the genome sequence. Our goals are to offer a reliable up-to-date resource on the genes, their functions, alternative variants, expression, regulation and interactions, in the hope to stimulate further validating experiments at the bench "> <meta name="author" content="Danielle Thierry-Mieg and Jean Thierry-Mieg, NCBI/NLM/NIH, [email protected]"> <!-- var myurl="av.cgi?db=mouse" ; var db="mouse" ; var doSwf="s" ; var classe="gene" ; //--> However I am stuck with the following script logic. What's the right way to achieve that? #!/usr/bin/perl -w my $INFILE_file_name = $file; # input file name open ( INFILE, '<', $INFILE_file_name ) or croak "$0 : failed to open input file $INFILE_file_name : $!\n"; my @allsum; while ( <INFILE> ) { chomp; my $line = $_; my @temp1 = (); if ( $line =~ /^ AceView summary/ ) { print "$line\n"; push @temp1, $line; } elsif( $line =~ /Please quote/) { push @allsum, [@temp1]; @temp1 = (); } elsif ($line =~ /The closest human gene/) { push @allsum, $line; } } close ( INFILE ); # close input file # Do something with @allsum There are many files like that I need to process.

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  • foreach loop corrupting my array?

    - by WmasterJ
    Explanation I have a multidimensional array that is iterated over to created a categorized view of people with different research interests. The main array look something like this: Array ( ... ['Cell Biology'] => Array(4 elements) ['Molecular'] => Array(6 elements) ['Biology Education'] => Array(14 elements) ['Plant Biology'] => Array(19 elements) <--- Last element in array ) I know that the entire array is intact and correctly structured. The only information that is inside these array is an user id, like so: Array ('Plant Biology') 19 elements ( [0] => 737 [1] => 742 [2] => 748 ... ) My problem is that after i run the main array through a foreach loop the last 'sub-array' gets messed up. By messed up I mean that what you see about instead look like: String (13 characters) 'Plant Biology' This is without doing at all anything inside the loop with to the array that gets corrupted. Any tips to what it might be? PHP Code // ---> Array is OK here echo "<h2>Research divided</h2>"; // Loop areas and list them in 2 columns foreach($research['areas'] as $area => $areaArray) { // ---> Here it is already corrupted $count = count($areaArray); if($count > 0) { echo "<h3>$area</h3><hr/>"; echo "<table class='area_list'><tr>"; // Loop users within areas, divided up in 2 columns for($i=0 ; $i<$count ; $i++) { $uid = $areaArray[$i]; echo "<li>$uid</li>"; } echo "</tr></table>"; } }

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  • Oracle Expands Sun Blade Portfolio for Cloud and Highly Virtualized Environments

    - by Ferhat Hatay
    Oracle announced the expansion of Sun Blade Portfolio for cloud and highly virtualized environments that deliver powerful performance and simplified management as tightly integrated systems.  Along with the SPARC T3-1B blade server, Oracle VM blade cluster reference configuration and Oracle's optimized solution for Oracle WebLogic Suite, Oracle introduced the dual-node Sun Blade X6275 M2 server module with some impressive benchmark results.   Benchmarks on the Sun Blade X6275 M2 server module demonstrate the outstanding performance characteristics critical for running varied commercial applications used in cloud and highly virtualized environments.  These include best-in-class SPEC CPU2006 results with the Intel Xeon processor 5600 series, six Fluent world records and 1.8 times the price-performance of the IBM Power 755 running NAMD, a prominent bio-informatics workload.   Benchmarks for Sun Blade X6275 M2 server module  SPEC CPU2006  The Sun Blade X6275 M2 server module demonstrated best in class SPECint_rate2006 results for all published results using the Intel Xeon processor 5600 series, with a result of 679.  This result is 97% better than the HP BL460c G7 blade, 80% better than the IBM HS22V blade, and 79% better than the Dell M710 blade.  This result demonstrates the density advantage of the new Oracle's server module for space-constrained data centers.     Sun Blade X6275M2 (2 Nodes, Intel Xeon X5670 2.93GHz) - 679 SPECint_rate2006; HP ProLiant BL460c G7 (2.93 GHz, Intel Xeon X5670) - 347 SPECint_rate2006; IBM BladeCenter HS22V (Intel Xeon X5680)  - 377 SPECint_rate2006; Dell PowerEdge M710 (Intel Xeon X5680, 3.33 GHz) - 380 SPECint_rate2006.  SPEC, SPECint, SPECfp reg tm of Standard Performance Evaluation Corporation. Results from www.spec.org as of 11/24/2010 and this report.    For more specifics about these results, please go to see http://blogs.sun.com/BestPerf   Fluent The Sun Fire X6275 M2 server module produced world-record results on each of the six standard cases in the current "FLUENT 12" benchmark test suite at 8-, 12-, 24-, 32-, 64- and 96-core configurations. These results beat the most recent QLogic score with IBM DX 360 M series platforms and QLogic "Truescale" interconnects.  Results on sedan_4m test case on the Sun Blade X6275 M2 server module are 23% better than the HP C7000 system, and 20% better than the IBM DX 360 M2; Dell has not posted a result for this test case.  Results can be found at the FLUENT website.   ANSYS's FLUENT software solves fluid flow problems, and is based on a numerical technique called computational fluid dynamics (CFD), which is used in the automotive, aerospace, and consumer products industries. The FLUENT 12 benchmark test suite consists of seven models that are well suited for multi-node clustered environments and representative of modern engineering CFD clusters. Vendors benchmark their systems with the principal objective of providing comparative performance information for FLUENT software that, among other things, depends on compilers, optimization, interconnect, and the performance characteristics of the hardware.   FLUENT application performance is representative of other commercial applications that require memory and CPU resources to be available in a scalable cluster-ready format.  FLUENT benchmark has six conventional test cases (eddy_417k, turbo_500k, aircraft_2m, sedan_4m, truck_14m, truck_poly_14m) at various core counts.   All information on the FLUENT website (http://www.fluent.com) is Copyrighted1995-2010 by ANSYS Inc. Results as of November 24, 2010. For more specifics about these results, please go to see http://blogs.sun.com/BestPerf   NAMD Results on the Sun Blade X6275 M2 server module running NAMD (a parallel molecular dynamics code designed for high-performance simulation of large biomolecular systems) show up to a 1.8X better price/performance than IBM's Power 7-based system.  For space-constrained environments, the ultra-dense Sun Blade X6275 M2 server module provides a 1.7X better price/performance per rack unit than IBM's system.     IBM Power 755 4-way Cluster (16U). Total price for cluster: $324,212. See IBM United States Hardware Announcement 110-008, dated February 9, 2010, pp. 4, 21 and 39-46.  Sun Blade X6275 M2 8-Blade Cluster (10U). Total price for cluster:  $193,939. Price/performance and performance/RU comparisons based on f1ATPase molecule test results. Sun Blade X6275 M2 cluster: $3,568/step/sec, 5.435 step/sec/RU. IBM Power 755 cluster: $6,355/step/sec, 3.189 step/sec/U. See http://www-03.ibm.com/systems/power/hardware/reports/system_perf.html. See http://www.ks.uiuc.edu/Research/namd/performance.html for more information, results as of 11/24/10.   For more specifics about these results, please go to see http://blogs.sun.com/BestPerf   Reverse Time Migration The Reverse Time Migration is heavily used in geophysical imaging and modeling for Oil & Gas Exploration.  The Sun Blade X6275 M2 server module showed up to a 40% performance improvement over the previous generation server module with super-linear scalability to 16 nodes for the 9-Point Stencil used in this Reverse Time Migration computational kernel.  The balanced combination of Oracle's Sun Storage 7410 system with the Sun Blade X6275 M2 server module cluster showed linear scalability for the total application throughput, including the I/O and MPI communication, to produce a final 3-D seismic depth imaged cube for interpretation. The final image write time from the Sun Blade X6275 M2 server module nodes to Oracle's Sun Storage 7410 system achieved 10GbE line speed of 1.25 GBytes/second or better performance. Between subsequent runs, the effects of I/O buffer caching on the Sun Blade X6275 M2 server module nodes and write optimized caching on the Sun Storage 7410 system gave up to 1.8 GBytes/second effective write performance. The performance results and characterization of this Reverse Time Migration benchmark could serve as a useful measure for many other I/O intensive commercial applications. 3D VTI Reverse Time Migration Seismic Depth Imaging, see http://blogs.sun.com/BestPerf/entry/3d_vti_reverse_time_migration for more information, results as of 11/14/2010.                            

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  • CodePlex Daily Summary for Friday, January 28, 2011

    CodePlex Daily Summary for Friday, January 28, 2011Popular ReleasesVFPX: VFP2C32 2.0.0.8 Release Candidate: This release includes several bugfixes, new functions and finally a CHM help file for the complete library.EnhSim: EnhSim 2.3.3 ALPHA: 2.3.3 ALPHAThis release supports WoW patch 4.06 at level 85 To use this release, you must have the Microsoft Visual C++ 2010 Redistributable Package installed. This can be downloaded from http://www.microsoft.com/downloads/en/details.aspx?FamilyID=A7B7A05E-6DE6-4D3A-A423-37BF0912DB84 To use the GUI you must have the .NET 4.0 Framework installed. This can be downloaded from http://www.microsoft.com/downloads/en/details.aspx?FamilyID=9cfb2d51-5ff4-4491-b0e5-b386f32c0992 - Added back in a p...DB>doc for Microsoft SQL Server: 1.0.0.0: Initial release Supported output HTML WikiPlex markup Raw XML Supported objects Tables Primary Keys Foreign Keys ViewsmojoPortal: 2.3.6.1: see release notes on mojoportal.com http://www.mojoportal.com/mojoportal-2361-released.aspx Note that we have separate deployment packages for .NET 3.5 and .NET 4.0 The deployment package downloads on this page are pre-compiled and ready for production deployment, they contain no C# source code. To download the source code see the Source Code Tab I recommend getting the latest source code using TortoiseHG, you can get the source code corresponding to this release here.Office Web.UI: Alpha preview: This is the first alpha release. Very exciting moment... This download is just the demo application : "Contoso backoffice Web App". No source included for the moment, just the app, for testing purposes and for feedbacks !! This package includes a set of official MS Office icons (143 png 16x16 and 132 png 32x32) to really make a great app ! Please rate and give feedback ThanksParallel Programming with Microsoft Visual C++: Drop 6 - Chapters 4 and 5: This is Drop 6. It includes: Drafts of the Preface, Introduction, Chapters 2-7, Appendix B & C and the glossary Sample code for chapters 2-7 and Appendix A & B. The new material we'd like feedback on is: Chapter 4 - Parallel Aggregation Chapter 5 - Futures The source code requires Visual Studio 2010 in order to run. There is a known bug in the A-Dash sample when the user attempts to cancel a parallel calculation. We are working to fix this.Catel - WPF and Silverlight MVVM library: 1.1: (+) Styles can now be changed dynamically, see Examples application for a how-to (+) ViewModelBase class now have a constructor that allows services injection (+) ViewModelBase services can now be configured by IoC (via Microsoft.Unity) (+) All ViewModelBase services now have a unit test implementation (+) Added IProcessService to run processes from a viewmodel with directly using the process class (which makes it easier to unit test view models) (*) If the HasErrors property of DataObjec...NodeXL: Network Overview, Discovery and Exploration for Excel: NodeXL Excel Template, version 1.0.1.160: The NodeXL Excel template displays a network graph using edge and vertex lists stored in an Excel 2007 or Excel 2010 workbook. What's NewThis release improves NodeXL's Twitter and Pajek features. See the Complete NodeXL Release History for details. Installation StepsFollow these steps to install and use the template: Download the Zip file. Unzip it into any folder. Use WinZip or a similar program, or just right-click the Zip file in Windows Explorer and select "Extract All." Close Ex...Kooboo CMS: Kooboo CMS 3.0 CTP: Files in this downloadkooboo_CMS.zip: The kooboo application files Content_DBProvider.zip: Additional content database implementation of MSSQL, RavenDB and SQLCE. Default is XML based database. To use them, copy the related dlls into web root bin folder and remove old content provider dlls. Content provider has the name like "Kooboo.CMS.Content.Persistence.SQLServer.dll" View_Engines.zip: Supports of Razor, webform and NVelocity view engine. Copy the dlls into web root bin folder to enable...UOB & ME: UOB ME 2.6: UOB ME 2.6????: ???? V1.0: ???? V1.0 ??Password Generator: 2.2: Parallel password generation Password strength calculation ( Same method used by Microsoft here : https://www.microsoft.com/protect/fraud/passwords/checker.aspx ) Minor code refactoringVisual Studio 2010 Architecture Tooling Guidance: Spanish - Architecture Guidance: Francisco Fagas http://geeks.ms/blogs/ffagas, Microsoft Most Valuable Professional (MVP), localized the Visual Studio 2010 Quick Reference Guidance for the Spanish communities, based on http://vsarchitectureguide.codeplex.com/releases/view/47828. Release Notes The guidance is available in a xps-only (default) or complete package. The complete package contains the files in xps, pdf and Office 2007 formats. 2011-01-24 Publish version 1.0 of the Spanish localized bits.ASP.NET MVC Project Awesome, jQuery Ajax helpers (controls): 1.6.2: A rich set of helpers (controls) that you can use to build highly responsive and interactive Ajax-enabled Web applications. These helpers include Autocomplete, AjaxDropdown, Lookup, Confirm Dialog, Popup Form, Popup and Pager the html generation has been optimized, the html page size is much smaller nowFacebook Graph Toolkit: Facebook Graph Toolkit 0.6: new Facebook Graph objects: Application, Page, Post, Comment Improved Intellisense documentation new Graph Api connections: albums, photos, posts, feed, home, friends JSON Toolkit upgraded to version 0.9 (beta release) with bug fixes and new features bug fixed: error when handling empty JSON arrays bug fixed: error when handling JSON array with square or large brackets in the message bug fixed: error when handling JSON obejcts with double quotation in the message bug fixed: erro...Microsoft All-In-One Code Framework: Visual Studio 2008 Code Samples 2011-01-23: Code samples for Visual Studio 2008MVVM Light Toolkit: MVVM Light Toolkit V3 SP1 (3): Instructions for installation: http://www.galasoft.ch/mvvm/installing/manually/ Includes the hotfix templates for Windows Phone 7 development. This is only relevant if you didn't already install the hotfix described at http://blog.galasoft.ch/archive/2010/07/22/mvvm-light-hotfix-for-windows-phone-7-developer-tools-beta.aspx.Community Forums NNTP bridge: Community Forums NNTP Bridge V42: Release of the Community Forums NNTP Bridge to access the social and anwsers MS forums with a single, open source NNTP bridge. This release has added some features / bugfixes: Bugfix: Decoding of Subject now also supports multi-line subjects (occurs only if you have very long subjects with non-ASCII characters)Minecraft Tools: Minecraft Topographical Survey 1.3: MTS requires version 4 of the .NET Framework - you must download it from Microsoft if you have not previously installed it. This version of MTS adds automatic block list updates, so MTS will recognize blocks added in game updates properly rather than drawing them in bright pink. New in this version of MTS: Support for all new blocks added since the Halloween update Auto-update of blockcolors.xml to support future game updates A splash screen that shows while the program searches for upd...StyleCop for ReSharper: StyleCop for ReSharper 5.1.14996.000: New Features: ============= This release is just compiled against the latest release of JetBrains ReSharper 5.1.1766.4 Previous release: A considerable amount of work has gone into this release: Huge focus on performance around the violation scanning subsystem: - caching added to reduce IO operations around reading and merging of settings files - caching added to reduce creation of expensive objects Users should notice condsiderable perf boost and a decrease in memory usage. Bug Fixes...New ProjectsAgilErp: AgilErp is a .NET OpenSource ERP - System developed in C# using WPF, WCF ,Entity Framework, MS-SQL-Server and MVVM. Angel Eye: 3d Game for the new generation AWWWE Browser: AWWWE Browser. (Pronounced "awe".) Aural World Wide Web Everywhere. 1) An aural browser. It talks and listens to you and you talk and listen to it. 2) A VUI for normal HTML web sites. It lets regular web sites talk and listen to you while you talk and listen to them.BitLocker Wrapper Library: The BDE Wrapper library allows .NET Developers to quickly use the WMI BitLocker provider without having to learn the complex methods and operation of the WMI classes.CRM8000: CRM8000????????????????DSM Hub for WP7: Implements a light version of the DSM tools for WP7. Currently, most of the effort is on the audio station.File Downloader: This application checks a Gmail account regularly for mail containing URLs. Once a URL is found, its content is downloaded and sent as a reply message with the file as an attachment. Intended usage: - Download IEEE articles as PDF when you're not in a authenticated network.Folder Space Quota: This component return Quotas Disk Space used for each folders and subfolders in a given directory. Results are returned with a graphic percent bar. Another Tab give access to this directory tree, indicating the size of each file and allows previewing them in a "LightBox" window. IDK: Every other month, IDK asks people to come up with awesome ideas for new programs and webpages. After the end of the month, IDKs developers have another month to create one of the top rated websites or applications. Got a great idea for a new app? Let IDK build it for you.Interop 2: Microformats for Azure Cloud with OData-InterfacejSPoint - JavaScript Library for SharePoint: JavaScript for SharePoint (jSPoint) is a library that help SharePoint developers to create rich,dynamic, & powerfull pages for SharePoint sites.MVVM T4: T4 Templates for generating view models, and views for WPF, Silverlight, Windows Phone using T4 Toolbox and MVVM LightNumericUpDown Control for WPF: A basic NumericUpDown Control for WPF that mirrors all the most used functions of the WinForms NumericUpDown Control and looks similar to itOData for IQToolkit: OData for IQToolkit, converts OData expressions into a usable expressions for IQToolkit providers.PLATO: PALTO is micro plate processing pipeline and supports enzymes and metabolites. PLATO was developed at INRA-Bordeaux and is an evolution of the EnzymeLaborTool developed at the Max-Planck Institute of Molecular Plant Physiology.Purdue CS 490: Model-based testing of ADO.NET: Five students from Purdue University will develop model-based tests for an aspect of ADO.NET during the Spring 2011 semester. We'll be using C# and Spec Explorer, among other tools.Replace in multiple Office 2010 documents: This program replaces a text string in multiple office 2010 documents (Word, Excel, PowerPoint). It is developed in VB.NET and new code for additional products is welcome. SearchEngine: A Website Search Engine and Crawler.Set Custom Currency Symbol: This utility enables you to set/register custom currency symbols for the .NET FrameworkSimple C# Email Templates: A really simple, really easy to use class for sending email templates. Reads any file from disk (think ".txt" or ".html") and matches custom tokens with the values you supply, in both the message body and the subject line. Supports multiple CC and BCC addresses.SimpleBasicAuthentication: SimpleBasicAuthentication makes it easier for developers to build a website with basic authentication using the credentials from just a text file. You'll no longer have to create new users on the system just to let them log in to the website or service. It's developed in C# 4.0.SpecsFor - Yet Another BDD Framework For .NET: SpecsFor is another Behavior-Driven Development framework that focuses on ease of use for *developers* by minimizing testing friction. Square: Custom SharePoint MyProfile PageSynchrolist workflow: Sharepoint workflow whitch perform automatic synchronisation between two lists in the same collection. Usefull for automatic translation.TFS Aggregator: This server side plugin for TFS 2010 enables dynamic calculation of field values in TFS. (For example: Dev work + Test Work = Total Work) Supports same work item and parent-child links. Also has support for aggregating string values (ie Children are Done so the parent is Done)Tinchant: My nice projectZebra_Image, a lightweight image manipulation library written in PHP: This is a compact (one-file only), lightweight, object-oriented image manipulation library written in and for PHP, that provides methods for performing several types of image manipulation operations. It doesn’t require any external libraries other than the GD2 extension.Zebra_Pagination, a generic pagination class written in PHP: A generic pagination class that automatically generates navigation links given the total number of items and the number of items per page.Zebra_Session, a wrapper for PHP’s default session handler, using MySQL: Zebra_Session is a PHP class that acts as a wrapper for PHP’s default session handling functions but instead of storing session data in flat files it stores them in a MySQL database, thus providing both better security and better performance.

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