In a little bit of a tech nightmare here. I know oodles about software, not so much more than the above average user about hardware.
I recently had to toss an old desktop of mine. It was gradually getting slower and slower, and after shutting the desktop down for long periods of time, it would choke up upon startup. Sometimes it'd give a disk read error, sometimes say no OS was found, etc. Restarting it about 5-15 times would eventually boot properly. Weird. I also noticed that startup programs were going missing, Dropbox was reindexing my entire folder, and Backblaze was backing up less than the number of files that it should. This lead me to believe it was probably a hard drive issue. I began to wonder why I'd have hard drive issues, and came to closure when I assumed it was because of recent power surges and outages. I'm sure that does a number on the drive.
I bought a new desktop recently. It's not a beast or anything, but it's enough for what I do. It's an eMachines (I know, I know) Ultra-Slim (http://www.amazon.com/eMachines-Ultra-Slim-ER1401-57-Desktop-PC/dp/B00475OG9U). This is ideal for me because it's small and portable. It comes with an AC adapter and battery, like a laptop. Just to be safe, I bought an uninterruptable power supply on top of that. It's basically protected completely from any outages that might scramble the drive.
I set this up a few days ago and for the past few days I've been perfecting settings, downloading the usual applications, etc. Two days ago, I noticed Dropbox was reindexing my entire Dropbox folder. I installed both Dropbox and Backblaze on this system, but it is very much more lightweight than the other. Only about 15 third-party applications installed. I thought that maybe Dropbox and Backblaze were stressing my system, so I turned off Backblaze. Still, Dropbox runs and comes across this infinite reindex issue. I noticed that upon a reboot recently, two applications did not start on startup either. Also, much like my old desktop, every 3rd or 4th reboot, I'll be forced into a chkdsk. This makes me incredibly nervous. What could possibly be going wrong with my old, years-old desktop that is immediately causing the same issues to my new one?
I've considered all of the basics. I'm in a very air conditioned room. I take run routine virus scans. I'd like to think I take care of my systems very well. What is this issue that is haunting me? There's always the possibility that this new desktop has a junk hard drive, but it just seems way too coincidental.