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  • Which is easier to learn, Zend Framework, CakePHP or CodeIgniter?

    - by Kwame Boame
    I am new to programming but I know HTML, CSS and Jquery. I am a web designer but want to expand my skill to application development with frameworks. Specifically, PHP frameworks. I want to know which of the frameworks mentioned in the question is difficult to master. Also, my friend wants me to learn Ruby on Rails/ Python instead of PHP. What's your best advice for a newbie programmer who is looking to build online software/apps in the near future; say, after 3 months/6 months or a year of study and practice?

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  • Imputing missing data in aligned sequences

    - by Kwame Oduro
    I want a simple perl script that can help me impute missing nucleotides in aligned sequences: As an example, my old_file contains the following aligned sequences: seq1 ATGTC seq2 ATGTC seq3 ATNNC seq4 NNGTN seq5 CTCTN So I now want to infer all Ns in the file and get a new file with all the Ns inferred based on the majority nucleotide at a particular position. My new_file should look like this: seq1 ATGTC seq2 ATGTC seq3 ATGTC seq4 ATGTC seq5 CTCTC A script with usage: "impute_missing_data.pl old_file new_file" or any other approach will be helpful to me. Thank you.

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  • What Java portal server do you use?

    - by bpapa
    I've been tasked with learning Vignette and setting it up is a nightmare. There are many different components in the wizard. If something fails, you get a cryptic error message and then have to start again. This is the worst "Wizard" since Kwame Brown. Are there other Portal servers out there that are easy to configure, or at least seem to have kept a developer's sanity in mind during configuration? To those that have used several different portal servers, which is your favorite?

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